The European project European and Latin American Systems of Ethics Regulation of Biomedical Research Project (EULABOR) has carried out the first comparative analysis of ethics regulation systems for biomedical research in seven countries in Europe and Latin America, evaluating their roles in the protection of human subjects. We developed a conceptual and methodological framework defining ‘ethics regulation system for biomedical research’ as a set of actors, institutions, codes and laws involved in overseeing the ethics of biomedical research on humans. This (...) framework allowed us to develop comprehensive national reports by conducting semi-structured interviews to key informants. These reports were summarised and analysed in a comparative analysis. The study showed that the regulatory framework for clinical research in these countries differ in scope. It showed that despite the different political contexts, actors involved and motivations for creating the regulation, in most of the studied countries it was the government who took the lead in setting up the system. The study also showed that Europe and Latin America are similar regarding national bodies and research ethics committees, but the Brazilian system has strong and noteworthy specificities. (shrink)

In this study we examine (1) how a manager’s risk behavior is influenced by developing success (or failure) as an impending settling up deadline to report performance approaches, (2) how willingness to provide transparent accountability is negatively affected by perceived risk and eroding trust, and (3) how others interpret and respond to reduced transparency. As perceptions of high levels of risks suggest a lack of environmental control of a firm’s destiny in contemporary settings, we adopt a historical approach to examine (...) these issues. In this respect we draw on primary sources found in library archives in Spain and Argentina. Our focal case refers to the contract signed and executed between the South Sea Company and Captain José de Salinas (1731–1735) to walk 408 Negroes from Buenos Aires to Potosí and sell them en route or at destination. Drawing on this evidence, we examine how bring about unethical conduct featured by increasingly risky business practices, and how eroding trust conditions lead to only summary record-keeping and delayed reporting. In turn, diminished accountability further undermined trust. Our findings have implications for further research in this area as well as for contemporary cases of accounting failures. (shrink)

Emotion inheres simultaneously in individuals and in the social structures and relationships in which individuals are embedded. Beginning with a critical examination of T.H. Marshall's account of class resentment, this paper considers the emotional patterns of resentment in class inequality, in trade cycle changes in costs and opportunities for income, and in class cultures. Arising from social relationships, emotion is the basis of action that subsequently affects the structure of social relationships. Thus emotion connects phases of social structure separated by (...) time. (shrink)

The main claim of this paper is that Plato's views on social and individual good as well as his criticism of democracy can be best understood as a conscious attempt to contrast with Periclean conceptions of freedom and democracy a new point of view. It will be argued that it is a mistake to see Plato's view as either democratic or authoritarian. An adequate understanding of Plato will focus on some difficult questions concerning the relationship between freedom and knowledge; questions (...) that are rarely if ever faced clearly today. The Platonic conception and its clash with Pericles raises also some important and still unresolved questions about human motivation. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS At the Origins of Modern Atheism. By MICHAEL J. BucKLEY, S.J. New Haven and London: Yale University Press, 1987. Pp. viii+ 445. Writing ostensibly a history of the philosophical origins of 18th century atheism in 17th century theism, Michael Buckley, S.J., has contributed a learned, subtle, and provocative hook whose length is significantly increased and whose focus is considerably enlarged by a running commentary about the metatheory (...) (Richard McKeon's philosophical semantics) that structures his reading of the chosen theists and atheists. Buckley provides the best summary of his own historical conclusion: "... theology generated apologetic philosophy and philosophy generated Universal Mechanics, and these in turn co-opted theology to become the foundations of theistic assertions... [But] when the contradictions between Cartesian and Newtonian mechanics were further negated... god became a deus otiosus" [pp. 358-359]. This conclusion rests on a philosophical principle whose elements are taken from Plato's Seventh Epistle: " The name, the definition, and the instance for the atheistic negations are all set by the current theism " [p. 15]. In turn, this principle is justified by a cluster of meta-theses that are not easily summarized, although one stands above the rest: " Much more may he involved in such a process of ideas [from 17th century theism to 18th century atheism] than their· own internal necessity, hut internal necessity remains and governs inherently " [p. 334]. The latter meta-thesis asserts that there is a dialectic of ideas and it is from this point of view that Buckley reads the conceptual history of modern atheism. Dialectical necessity is a bugbear for many contemporary philosophers, hut Buckley argues, convincingly I think, that some kind of conceptual necessity links theism and atheism. Atheism is, essentially, the negation of a particular form of theism. In Hegelian terms, atheism is a determinate negation which draws all of its conceptual content from what it negates. Buckley, however, puts an even greater Hegelian spin on the same point. If the theism carries within itself a contradiction, it negates itself and, thereby, dialectically generates its contradiction-atheism [cf. p. 17]. " Modern atheism took not only its meaning hut its existence from the self-alienation of religion " [p. 359]. A theism that believes in the existence of an intelligent, personal God, Who creates and orders the universe, but that attempts a rational 144 BOOK REVIEWS 145 justification of this belief apart from the religious experience that alone can embody such a faith contains exactly the kind of inner contradiction that generates the negation of itself. Buckley focuses on the poignant contradiction of a Christian theology abandoning " the religious figure of Jesus as the principal evidence for the reality of God" [p. 41] in favor of some philosophy (whether that of Descartes, Malebranche, or Newton) which provides a different and allegedly more certain kind of evidence for God's existence. This theology, or more precisely the theistic philosophies it spawned, are the sources of modern atheism because, if Descartes and Newton are consistently combined, philosophy can do quite well without God. Laplace's famous reply to Napoleon, although it was not originally an atheistic slogan, captures what Diderot and d'Holbach thought: God is an unnecessary hypothesis in a truly universal mechanics which needs to presuppose only matter and motion. The historical story, of course, is more complicated than this skeleton dialectic can suggest. Buckley richly details the story but I shall rehearse only its opening chapter. Buckley begins with the Jesuit theologian, Leonard Lays (1554-1623), usually known under his Latin name, Lessius, whose De providentia numinis et anima immortalitate (1613) set the pattern for subsequent Catholic theology. Lessius, who was convinced that atheism by eliminating the eternal judge destroys morals and sound politics, revived Stoic arguments, numerous variations on a theme, which show that the universe is everywhere imprinted with a divine design. Lessius's intent, although he referred only to ancient philosophers, was not to replay the classical battle between the Stoics and the Epicureans but to combat the atheism, silent and disguised in contemporary Europe, that Lessius thought to be the inevitable outcome of the wars of religion and theological fights. Lessius, however, paid scant attention to his own insight... (shrink)